Synthesis, Characterization, Antibacterial Activities of Novel Polydentate Schiff’s Bases and Their Transition Metal Complexes

The work described in this thesis concerns the synthesis of six novel new polydentate Schiff's bases and the formation of their Metal Complexes with copper bromide and cadmium chloride. The ligands and their metal complexes were characterized by IR, UV-VIS spectroscopy, EA, 1H-NMR ,13C-NMR, TG/DTA. The structure of free ligand. L5(N1E,N2E)-N1,N2-bis((5-bromothiophen-2-yl)methylene)ethane-1,2-diamine & L3[(N1E,N2E)-N1,N2-bis(2-chlorobenzylidene)cyclohexane-1,2-diamine] analyzed by XRD. The potential of the ligands and their copper complexes against E. coli, S. aureus, P. aeruginosa, and MRSA bacteria were studied. So we expected to introduce to the literature a novel chemotherapy (antibacterial) drugs.